CURRICULUM VITAE

Undergraduate:

Centre College of Kentucky

Danville, KY

1966-69

Medical School:

University of Kentucky

Lexington, KY

1969-73

Internship:

Miami Valley Hospital

Dayton, OH

1973-74

Residency (Urology):

Michigan State University

East Lansing, MI

1974-75

Medical University Of South Carolina

Charleston, SC

1975-78

Kentucky Board of

Medical Licensure:

No. 19237

Residency Honors:

Southeast Section, American Urological Association Montague L. Boyd Prize Essay Contest in Laboratory Research, Second place. 1977.

Southeast Section, American Urological Association Montague L. Boyd Price Essay Contest in Clinical Research, First Place. 1978

AUA Board Written Exam:

99^th percentile of 300 candidates

May 1978

American Board of Urology:

Diplomat, February 1980

Southeastern Section of American Urological Association:

Member, April 1980

American College of Surgeons:

Fellow, 1982

Boston University School of Medicine:

Erectile Dysfunction,

Special Fellowship, Aug. 1987-89

Mayo Clinic, Rochester, Minnesota:

General Urologic Laser

Applications, 1988

Humana Impotency Research and

Study Group:

Secretary, 1987-91

Humana Hospital-Lexington:

Chief, Department of Surgery 1988

Mobile Urology Group:

Prostate Ultrasonography

William Cooner, M.D.

Tutorialship, June 1991

Humana Hospital-Lexington:

Chief, Department of Surgery, 1991

Medical Seminar Group:

Certification, Laser Prostate

Ablation, 1992

CERTIFICATION CENTER:

Procedures for Treatment of Benign

Prostate Hyperplasia, January 15, 1993

For Visual Laser Ablation

of the Prostate

COLLAGEN IMPLANT CERTIFICATION:

Contigen Implant Preceptorship

Dr. Rodney Appell

Cleveland Clinic, Cleveland, OH

March 1994

HOLMIUM LASER CERTIFICATION:

Oakland, California, July 1994

POST-GRADUATE COURSES:

Faculty

Dual Wave Laser Prostatectomy

Durham, NC – 8 Hours C.M.E.

Didactic And Animal Laboratory

March 1993

Visual Laser Ablation Prostate

Dual Wave Laser Prostatectomy

Instructional Forum And Video Tape

American Urologic Association

Annual Meeting, San Antonio, TX

May 1993

Dual Wave Laser Prostatectomy

St. Louis, MO – 4 Hours C.M.E.

Didactic and Animal Laboratory

May 1993

Current Treatment Strategies for

Benign Prostatic Hyperplasia.

Harlan County Medical Society -

1 Hour C.M.E. Harlan, KY

June 1993

Consensus Panel for Abbott

Pharmaceutical – 8 Hours C.M.E.

Abbott Park, Chicago, IL

August 1993

Current Treatment Strategies for

Benign Prostatic Hyperplasia -

1 Hour C.M.E. Abbott Pharmaceuticals

Lexington, KY

November 1993

Dual Wave Laser Prostatectomy

Didactic and Animal Laboratory -

8 Hours C.M.E. San Francisco, CA

September 1993

Dual Wave Laser Prostatectomy

Visiting Instructor and Proctor -

4 Hours C.M.E. Baptist Hospital

Louisville, KY

December 1993

Dual Wave Laser Prostatectomy

Honorary Faculty Member

Vancouver General Hospital

Teaching Center – 8 hours C.M.E.

Vancouver, British Columbia

January 1994

Dual Wave Laser Prostatectomy

Wayne State University – 8 hours C.M.E.

Detroit, MI

January 1994

Dual Wave Laser Prostatectomy

Fredricksburg, VA Proctorship

Fredricksburg, VA

August 1994

Medical Management of

Symptomatic BPH - 1 Hour C.M.E.

Cincinnati, OH

February 1995

Use of Neodymium: YAG/KTP-532

Dual Wave Laser Prostatectomy

In Private Practice Setting and

Instructional Course.

Honorary Faculty Member

Bangkok General Hospital

Bangkok, Thailand

March 1995

Hytrin Community Assessment Trial

(HYCAT)

Abbott Davos Winter European

Congress Forum – 8 Hours C.M.E.

Davos, Switzerland

February 1996

POST-GRADUATE PRESENTATION:

Dual Wave Laser Prostatectomy

1 Year Follow-Up. American Urologic Association Annual Meeting.

San Francisco, CA

May 1994

Live Laser Prostatectomy

Moderator With Ralph Benson, M.D.

Summit Medical Center

Oakland, CA

May 1994

Broadcast to American Urologic

Association Annual Meeting.

San Francisco, CA

May 1994

EMPI Pelvic Floor Electric Stimulation:

A Comparison of Two Treatment

Protocols in Female Genuine Stress

Incontinence: D.A. Richardson,

K.L. Miller, S.W. Siegel, M.M. Karram,

N. Blackwood and J. P. Tuttle, ACOG.

May 1995

Bull Prostate Model Laser Prostatectomy

Demonstration – American Urologic Association Meeting.

Las Vegas, NV

May 1995

Overactive Bladder Syndrome. Presented to Puerto Rico Urologic Association Semi-Annual Meeting

Ponce, Puerto Rico, 1999

IMPOTENCY CONSENSUS PANEL:

Consensus Panel Updating PGE1 Intracorporeal Infections in the Future of Erectile Dysfunction Treatment.

Upjohn Pharmaceuticals

Amelia Island, FL

October 1994

PRESENTATION: Terazosin HCL vs Placebo in HYCAT

Trials as Related to Changes in PSA,

HYCAT Consensus Panel

Key Largo, FL

November 1994

Formal Presentations:

*Original Research

Mesotheliomas Of Spermatic Cord. Read At Annual Meeting Of Southeastern Section, American Urological Association, Hollywood, FL 1976.

*Interference Of Human Spermatozoal Motility And Spermatozoal Agglutination By Candida Albicans. Read At Annual Meeting Of Southeastern Section, American Urological Association, New Orleans, LA 1977.

*The Role Of Vaginal IgA In Pediatric Patients With Recurrent Urinary Tract Infections. Read At Annual Meeting Of Southeastern Section, American Urological Association, Louisville, KY 1978.

Tuttle, JP and Sander, J: Special On Male Sexual Impotency. CBS, WKYT-TV, Lexington, KY 1998.

Sexual Impotency In Diabetic Men. Diabetes Center of Excellence Forum. Humana Hospital-Lexington, Hyatt Regency, Lexington, KY 1988.

Tuttle, JP, Borges, FD, Fitch, WP, Geller, RA, Hubbard, JG, Kaufman, JM, McKay, DL, Witten, FR,: Evaluating Pelvic Trauma As The Cause Of Erectile Dysfunction. Read At Annual Meeting HIRSG, Phoenix, AZ 1991.

Alpha I Mentor Prosthesis In 101 Consecutive Cases. Poster Session, American Urological Association Annual Meeting, Toronto, Canada 1991.

Fitch, WP, Tuttle, JP, et al: Microsurgical Arterial Bypass Surgery In 123 Consecutive Cases (HIRSG), Read At International Society Of Impotency Research, Milan, Italy 1992.

Fitch, WP, Borges, FD, Tuttle, JP, et al: Surgical Treatment Of Penile Veno-Occlusive Insufficiency. Read at International Society of Impotency Research, Milan, Italy 1992.

Fitch, WP, Borges, FD, Tuttle, JP: Vascular Risk Factors. Read at International Society of Impotency Research, Singapore, Malaysia 1994.

Goldstein, I, Albrecht, D, Kaufman, J, Tuttle, JP, Castellanos, R, Fitch, W, Gittelman, M, Auerback, S, Padma-Nathan, H, Rajfer, J, and Nelson, L: Multi-institutional Prospective with Intracavernosal Alprostadil Alfadex; 12-month Follow-up. Read at the Annual Meeting American Urological Association, New Orleans, LA 1997.

Albrecht, D, Goldstein, I, Kaufman, J, Tuttle, JP, Castellanos, R, Fitch, W, Gittelman, M, and Alprostadil Alfadex Study Group: Placebo-Controlled Double-blind Study of Alprostadil Alfadex for Intracavernosal Self-injection Therapy at Home. Read at the Annual Meeting American Urological Association, New Orleans, LA 1997.

Cohn, M, Gittelman, M, McRae, J, Tuttle, JP, Zucker, I, Donatucci, C, Knoll, D, Nelson, R, and Young, P: Quality of Life Results of Patients and Partners on the Vivus-MUSE Study Group. Read at the Annual Meeting Southeastern Section, American Urological Association, Naples, FL 1997.

Tuttle, JP, Knoll, D, Schmidt, R, Susset, J, and Zinner, N: Cost Effectiveness of

Ditropan XL Treatment for Urge Incontinence. Read at the Annual Meeting American Urological Association, Dallas, TX 1999.

Tuttle, JP, et al: Ditropan XL Tolerability in the Elderly. Poster Session, Geriatric Association, Nashville, TN, May 2000.

Tuttle, JP: Effect of Controlled Release Oxybutynin and Tolterodine on Salivary Output. Read at the New York Section of the American Urological Association Annual Meeting, Cape Town, South Africa, October 2000.

Tuttle, JP: One-Year, Prospective, Open Label Trial of Controlled Release Oxybutynin on Overactive Bladder in a Community-Based Application. Read at the New York Section of the American Urological Association Annual Meeting, Cape Town, South Africa, October 2000.

PUBLICATIONS:

Tuttle, JP and Rous, SN: Urinary Retention and Hydronephrosis in a Child Caused by Contact Dermatitis of External Genitalia. Urol., 5:252, 1975.

Tuttle, JP, Rous, SN and Kinsel, RC: Bladder Epithelial Neoplasms Meatatatic to Glans Penis. Urol., 8:80, 1976.

Tuttle, JP, Bannister, ER and Derick, FC: Interference of Human Spermatozoal Motility and Spermatozoal Agglutination by Candida Albicans. J Urol., 118:797, 1997

Tuttle, JP, Pratt-Thomas, WB: Embryonal Carcinoma of the Testis in Elderly Men. J. Urol., 118:1070, 1977.

Tuttle, JP, Holbrook, TW and Derick, FC: Interference of Human Spermatozoal Motility by Trichomonas Vaginalis. J Urol., 118:1024, 1977.

Tuttle, JP, Sarvas and Koistinen: The Role of Vaginal IgA in Pediatric Females with Recurrent Urinary Tract Infections. J Urol., 120:742, 1978.

Tuttle, JP: Sexual Response to Cancer (Letter to Editor), CA-A Cancer Journal for Clinicians, 38:3, 1988.

Tuttle, JP: Impotency-Clinical Update. Impotency Diagnostic and Treatment Services. Humana Hospital, Lexington, KY, September 1988.

Tuttle, JP: Impotency-The Quiet Problem. Humana Hospital, Lexington, KY October 1988.

Goldstein, I, Bereto, EB, Kaufman, JM, Witten, FR, Hubbard, JG, Fitch, WP, Geller, RA, McKay, DL, Krane, RH, Borges, FD, Babayan, RK, Tuttle, JP, Gruber, MB, Harik, V and Levinson, S: Early Experience with the First Pre-Connected 3-piece Inflatable Penile Prosthesis: The Mentor Alpha-I. J Urol., 150:1814, 1993.

Kaufman, JM, Borges, FD, Fitch, WP, Geller, RA, Gruber, MB, Hubbard, JG, McKay, DL, Tuttle, JP and Witten, FR: Evaluation of Erectile Dysfunction by Dynamic Infusion Cavernosometry and Cavernosography (DICC)
. Urology 41:445, 1993.

Tuttle, JP: VLAP-Laser Practice Record. Clinical Laser Monthly, 11:187, 1993.

Tuttle, JP: New Solutions in Prostate Surgery. Health Harbinger, 9, No. 1, 1993.

Roehrborn, CG, Oesterling, JE and the HYCAT Investigator Group (Tuttle, JP): The Hytrin Community Assessment Trial Study: A One Year Study of Terazosin Versus Placebo in the Treatment of Men with Symptomatic Benign Prostatic Hyperplasia. Urol., 47:159, 1996.

Hillman, AL, Schqartz, JS and the HYCAT Investigator Group (Tuttle, JP): The Cost Effectiveness of Terazosin and Placebo in the Treatment of Moderate to Severe Prostatic Hyperplasia. Urol., 47:169, 1996.

Bellin, P, Smith, J, Poll, W, Sergel, B, Knoll, D, Childs, S, Tuttle, J, Barda, J and Dann, J: Results of a Multicenter Trial of the Capsure Continence Shield on Women with Stress Urinary Incontinence. Urol., 51:697, 1998.

Millard, R, Tuttle, J, Moore, K, Susset, J, Clarke, B, Dwger, P and Davis, B: Clinical Efficacy and Safety of Tolterodine Compared to Placebo in Detrusor Overactivity.

J. Urol., 161:155, 1999.

RESEARCH GRANTS:	1991	Phase IV Study, Ciprofloxacin HCl.
	1992-93	Phase IV Study, Proscar.
	1992-93	Phase III Study, Hytrin.
	1992	Phase III Study, Alprostadil (PGE1) Sterile Powder.
	1993	Prospective Study of the Oral versus Written AUA Symptom Index for Benign Prostate Hyperplasia.
	1993	Anticancer Drug Therapy Recording.
	1993	Phase III Study, Alprostadil Alphadex.
	1993	Phase III Study, Erectile Dysfunction.
	1993	Phase III Device Testing, Vaginal Electrostimulation in the Management of Enuresis.
	1993	Phase III Study, Lupron.
	1993	Phase III Study, Doxazosin.
	1993	Phase II Study, AD-32.
	1994	Phase III PGE1 Intracavernosal Injection versus Vacuum Device.
	1994	Phase III Study, Levofloxacin versus Lomefloxacin HCl.
	1994	Phase IV Study, KTP/532/Neodymium yag versus Neodymium yag VLAP.
	1994	Phase III Study, MUSE System for Men with Erectile Dysfunction.

1994

Serum for Biomarkers. Description: Evaluation of Biomarkers in the Diagnosis and Management of

Prostate Disease.

1995

Phase II Study (A9301): Intravesical

AD-32 in Patients with Carcinoma In Situ of the Bladder Who Have Failed Or Have Recurrence Following Treatment with BCG.

1995

Phase III Study, Treatment of Complicated Urinary Tract Infections.

1995

Phase II Study, Erectile Dysfunction.

1995

Phase II Study, Levofloxacin.

1995

Magnetic Valve for Incontinent Women.

1995

Phase II Study, Tolterodine.

1995

Phase IV Study, Lupron in Intermittent Versus Continuous Androgen Deprivation.

1995

Urethral Dilatation and KTP/532 Laser Coagulation for the Treatment of Trigonitis Comparative Study.

1995

Phase IV Study, International Douche versus Wipe.

1996

Phase II Study, Oxybutynin Patch (YYS) and OROS Capsule in Urinary Incontinence.

1996

Phase II Study, Duloxetine Hydrochloride.

1996

Phase III Study, Testosterone Transdermal Symptoms in Impotency.

1996

Phase III Study for BPH.

1996

Phase III Study, Trovafloxacin.

1996

Phase II Study, Duloxetine in Urinary Incontinence.

1996

Phase II Study, Urinary Incontinence.

1996

Phase III Study, Minimal Erectile Dysfunction.

1996

Phase III Study, Injection for Men with Insuline Dependent Diabetes.

1997

Phase III Study, Urethral Device Study in Women with Urinary Stress Incontinence.

1997

Phase III Study, Erectile Dysfunction.

1997

Infusion for Bone Pain in Men with Prostate Cancer and Bone Metastasis.

1997

Phase III Study, Minimal Erectile Dysfunction.

1997

Phase III Study, Minimal Erectile Dysfunction.

1997

Phase IV Study, MUSE and Actus (Venous Flow Controller) in Men with Erectile Dysfunction.

1997

Phase III Study, Treatment and Prevention of Progression of BPH.

1997

Phase II Study, Continuous Infusion for 30-60 days in Patients Undergoing Radiation Therapy with Interstitial Seed Implant.

	1997	Phase III Study, Complicated UTI’s and Pyelonephritis.
	1997	An Open Non-Comparative Extension Study of Sildenafil in Patients with Erectile Dysfunction.
	1997	Phase III Study, Erectile Dysfunction.
	1997	Phase III Study, Multiple Superficial Bladder Tumors.
	1998	Phase III Study, Complicated UTI’s in Adults.
	1998	Post Approval Study, UroLume Endoprosthesis for the Treatment of Prostatic Obstruction.
	1999	Phase IV Study, Long Term Safety Study, Erectile Dysfunction.
	1999	Phase III Study, Open Label BPH.
	2000	Phase IV Study, Urge Incontinence Men and Women.
	2000	Phase IIIB Study, Urge Incontinence Men and Women.
	2000	Phase III Study, Urge Incontinence Men and Women.
	2000	Phase IV Study, Community-Based, Urge Incontinence Men And Women.

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