CURRICULUM VITAE

CURRICULUM VITAE

Irvin Hirsch, M.D.

OFFICE:

Department of Urology

Jefferson Medical College

1025 Walnut Street

Philadelphia, PA 19107

(215) 955-6961 - Telephone

(215) 923-1884 - Fax

Dr. Hirsch is an Associate Professor at Jefferson. He has directed Jefferson's efforts in male infertility and sexual dysfunction since joining the Urology faculty in 1985. Since then, he has been committed to advances in microsurgical, laser, laparoscopic, and medical treatments of disorders specific to men's health. His research interests have lead to advances in clinical and scientific aspects of Male Reproductive Rehabilitation. He serves as a reviewer for the Journal of Urology, Journal of Andrology, and other professional journals and has published extensively in his fields of interest. He is the Pennsylvania Medical Advisor for the Impotence Institute of America. Dr. Hirsch has been cited among the "Best Doctors in America" and is a member of many organizations in urology, fertility and impotence.

ACADEMIC:

The City College

School of Engineering B.E. Electrical, 1974

New York, New York

Mount Sinai School of Medicine

New York, New York M.D., 1979

Baylor College of Medicine Fellow, Male Reproductive

Houston, Texas Medicine and Surgery, 1985

Fellow, Urodynamics and

Uroprosthetics

POSTGRADUATE TRAINING:

Resident: General Surgery 1979 - 1981

C.K. McSherry, M.D., Department Chairman

Beth Israel Medical Center

New York, New York

Resident: Urology

Elliot Leiter, M.D., Department Chairman 1982 - 1984

Beth Israel Medical Center

New York, New York

Chief Resident: Urology 1983 - 1984

Beth Israel Medical Center

New York, New York

Fellow:

Male Reproductive Medicine and Surgery 1984 - 1985

Larry I. Lipshultz, Program Director

Baylor College of Medicine

Houston, Texas

Urodynamics and Uroprosthetics 1984 - 1985

E. Brantley Scott, Program Director

Baylor College of Medicine

Houston, Texas

CERTIFICATION AND LICENSURE:

National Board of Medical Examiners 1980

New York State 1980

Commonwealth of Pennsylvania (MD-033826-E) 1987

American Board of Urology 1988

American Board of Urology, Recertification 1996

PROFESSIONAL SOCIETY MEMBERSHIPS:

Society for the Study of Male Reproduction

American Spinal Cord Injury Association

American Urological Association Society of Reproductive Surgeons

Mid-Atlantic Section of the American

Urological Association

American College of Surgeons

Urodynamics Society

International Society for Impotence Research

American Society of Andrology Society of Cryobiology

The Philadelphia Area Reproductive

Endocrinology Society

American Congress of Rehabilitation Medicine

American Association of Tissue Banks

Philadelphia Urologic Association

Pennsylvania Medical Society

American Medical Association Medical Society of the State of New York

Medical Society of the County of New York

Associated Alumni of the Mount Sinai Hospital

and Mount Sinai School of Medicine

Eta Kappa Nu (Electrical Engineering)

Tau Beta Pi (Engineering)

Society for the Study of Male Reproduction

COMMITTEES OF NATIONAL ORGANIZATIONS:

Urology Committee, American Spinal Injury Association

National Task Force on Sexuality and Disability

Regional Medical Advisor (Pennsylvania), Impotence Institute of America

Abstract Committee, American Society for Reproductive Medicine

Executive Committee, Philadelphia, Urological Society

Committee On Complementary and Alternative Medicine, American Urological Association

ACADEMIC APPOINTMENTS:

Clinical Professor of Urology

Jefferson Medical College

Philadelphia, Pennsylvania 1997 - present

Associate Professor of Urology 1990 - 1997

Jefferson Medical College

Philadelphia, Pennsylvania

Assistant Professor of Urology 1985 - 1990

Jefferson Medical College

Philadelphia, Pennsylvania

Instructor in Urology 1984 - 1985

Baylor College of Medicine

Houston, Texas

Instructor in Urology 1983 - 1984

Mount Sinai School of Medicine

New York, New York

HOSPITAL APPOINTMENTS:

Department of Urology

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

The Prostate Center

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Urologic Consultant

Magee Rehabilitation Hospital

Philadelphia, Pennsylvania

Urologic Consultant

Wilmington Veterans Administration Hospital

Wilmington, Delaware

Urologic Consultant

Sexual Function Center

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

HOSPITAL APPOINTMENTS (cont):

Urologic Consultant

Comprehensive Rectal Cancer Center

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Urologic Consultant

Multiple Sclerosis Center

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Urologic Consultant

Sleep Disorders Center

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Staff Urologist

Jefferson Park Hospital

Philadelphia, Pennsylvania

JEFFERSON MEDICAL COLLEGE ACTIVITIES:

Committee on Curriculum

Geriatrics Advisory Committee

Liaison Committee on Medical Education

Urology Resident Evaluation and Review

Course Coordinator; IDEPT-470 - Urology

Course Coordinator; Contemporary Issues in Medicine, Sophomore Seminar Series

Medical Student Advisor

Career Planning Program Committee

Family Medicine Residency Preceptor

Lecturer; Pathology 401-Advanced Basic Sciences Course

Lecturer; Freshman Introduction to Clinical Medicine

Lecturer; Applied Pharmacology #402

Lecturer; IDEPT-470

Urology Lecturer; Contemporary Issues in

Medicine, Sophomore Seminar Series

Director, Undergraduate Medical Education

THOMAS JEFFERSON UNIVERSITY HOSPITAL ACTIVITIES:

Committee on Materials and Standardization

Tissue Committee

Quality Assurance Committee

JEFFERSON PARK HOSPITAL ACTIVITIES:

Education Committee

First Prize, Doctors Alumni Association Essay

HONORS AND PRIZES:

Contest, Beth Israel Medical Center, 1983

Second Prize, Laboratory Research, Ferdinand C.

Valentine Residents Essay Contest, 1983

HONORS AND PRIZES (cont):

(Sponsored by the New York State Section of the

American Urological Association and the Section

on Urology of the New York Academy of Medicine)

Best Doctors in America (Northeast Region), 1996- 1997

Who’s Who in Science and Engineering (IVth Edition), 1997

Speakers Bureau, Pfizer Pharmaceuticals, 1998

Speakers Bureau, SmithKline Beacham, 1998

Speakers Bureau, Boehringer Ingelheim, 1998

Distinguished Visiting Faculty, Overactive Bladder Series, Pharmacia and Upjohn , 1998

Outline Consultant, Health Philadelphia, Philadelphia Online, 1998

Top Docs for the Aging, Philadelphia Magazine, June1998

Speakers Bureau, ALZA Pharmaceuticals, 1999

MEDIA ENGAGEMENTS

Philadelphia Inquirer: "Viagra Issues", April 22, 1998

Channel 29: "Viagra Issues", April 23, 1998.

Channel 6: "Men's Health Issues", May 6, 1998

Channel 10: "Viagra Safety", May 22, 1998

KWY NEWS Radio: First anniversary of Viagra release, March 27, 1999

WPEN 950 AM: "Diabetes, Medicare and Health Matters"

Daily News: "First anniversary of Viagra release", May 27, 1999

Pittsburgh Post Gazette: "There's More to Erectile Dysfunction than just Viagra", Op - Ed,

Health Section, June 15, 1999.

Philadelphia Inquirer: The Change in Treatment of Older Men

Business Section, June 28, 1999

SPONSORED RESEARCH

1. Double-blind randomized placebo-controlled dose ranging study of Atamestane to evaluate the efficacy, safety, and endocrinologic effects in symptomatic patients with benign prostatic hyperplasia. Berlex Laboratories, Wayne, New Jersey ($51, 304),

(Primary Investigator) 1990 - 1991.

2. A phase-II dose finding placebo-controlled study of four dose levels of YM-617 in patients with signs and symptoms of benign prostatic hyperplasia. Oxford Pharmaceutical Services, Clifton, NJ ($60, 000), (Primary Investigator) 1990 - 1991.

3. Male reproductive rehabilitation with electroejaculation. Medlantic Corporation, Washington, DC, (Primary Investigator) 1990 - present.

4. Imaging and assessment of urethral wall Collagen injection. C.R. Bard, Inc., Covington, GA ($2, 000), (Co-investigator).

5. Prospective randomized study of transurethral balloon dilatation versus external sphincterotomy in spinal cord injured men. Department of Urology and Rehabilitation Medicine, Jefferson Medical College, (Co-Investigator).

6. A fourteen-week, double-blind, placebo-controlled, dose-response study using Doxazosin tablets for the treatment of benign prostatic hyperplasia in normotensive patients. Pfizer Pharmaceuticals, New York, NY ($96, 518), (Primary Investigator) 1992.

7. UroLume Wallstent prostatic application clinical study. American Medical Systems

($15, 000), (Co-Investigator).

8. Pilot study with sterile powder (S. Po.) Alprostadil (Prostaglandin E-1, PGE-1) in patients with erectile dysfunction. Upjohn Company, Kalamazoo, MI ($109, 425), (Primary Investigator), 1992- 1993.

9. Neurological recovery of bladder and erectile function after spinal cord injury. National Rehabilitation Research and Training Center in Spinal Cord Injury

(Co-Investigator).

10. Transurethral UroLume Wallstent: Urethral Stricture Clinical Application, American Medical Systems, Jefferson Medical College (Co-Investigator).

11. Spermatogenesis following experimental spinal trauma, Nemours Research Foundation, Alfred I. duPont Institute. unfunded (Principal Investigator).

12. Transurethral UroLume Wallstent: Prostate Clinical Application, American Medical Systems, Jefferson Medical College (Co-Investigator).

13. Transurethral UroLume Wallstent: Sphincter Clinical Application, American Medical Systems, Jefferson Medical College (Co-Investigator).

14. Spermatogenesis Following Spinal Cord Injury: Quantitative and Dynamic Assessment in the Rat Model. Spinal Cord Research Foundation (Paralyzed Veterans of America), Washington, DC ($41, 900) (Primary Investigator) 1994- 1995.

15. Multi-center efficacy and tolerability study comparing Proscar (Finasteride) and placebo in the treatment of symptomatic benign prostatic hyperplasia in a primary care setting. Merck, Inc., West Point, PA (Sub-investigator/Consulting Urologist) 1995.

16. Detection and hedonic rating of the smell of Androsterone in young adult men with insufficient spermatogenesis (unfunded) 1995.

17. Testicular microlithiasis and infertility (unfunded) 1996.

18. Correlates of fertility in spinal cord injured men. National Institutes of Health (participating clinical center ) 1994 - 1997.

19. A Randomized, Double-Blind, Placebo-Controlled, Two Year Parallel Group Study of the Efficacy And Safety Of GI198745 0.5 MG In The Treatment And Prevention Of Progression Of Benign Prostatic Hyperplasia. Glaxo Wellcome, Inc. (Co-Investigator) 1997 - 1998.

20. A Phase III At Home Use Study Evaluating the Efficacy and Safety of Escalating Doses of Uprima ^TM SL 2, 3, and 4 mg in the Treatment of Patients with Erectile Dysfunction. (Principal Investigator). TAP Holdings, Inc., 1999.

21. An Open-label Trial of Vasomax^TM (Oral Phentolamine) in Spinal Cord Injured Patients with Mild to Moderate Erectile Dysfunction" (Principal Investigator), Schering Inc., 1999.

22. A Phase-III at Home Use Study Evaluating the Efficacy and Safety of Escalating Doses of Uprima™ (Apomorphine HCL Tablets) 2,3 and 4mg in the Treatment of Patients with Erectile Dysfunction. (Principal Investigator). TAP Holdings, Inc. 1999.

23. A Phase III, Dose Finding, Placebo-Controlled, Double-Blind Study of Fixed Levels of KMD-3213 in Patient with the Signs and Symptoms of Benign Prostatic Hyperplasia (BPH). (Co-investigator). Kissei USA, Inc., 1999.

24. Phase I and II Trial of Selenium and Prostate Cancer. National Cancer Institute, #CA79089. (Principal Investigator). ($791,471; Participating Center). 1999.

25. Chemoprevention Trial of Selenium and Prostate Cancer. Department of Defense, #DAMD 17-98-1-8580. (Principal Investigator). ($193,416; Participating Center). 1999.

26. Phase III Trial of Selenium and Prostate Cancer Prevention. National Cancer Institute #CA77789. (Principal Investigator). ($1,086,286; Participating Center). 1999.

27. A Post-Market Clinical Study Evaluating the Uroflow, PVR, and Symptoms. Alleviation of Water Induced Thermotherapy with the Thermoflex System. (Co-Investigator). ArgoMed, Inc., 2000.

ORIGINAL MANUSCRIPTS (peer reviewed)

1. Hirsch, I.H. and Reddick, J.: Improved design of electrophoretic equipment for rapid sickle cell anemia screening. NASA Tech Brief 10025, Goddard Space Flight Center, National Aeronautics and Space Administration, April, 1974.

2. Hirsch, I.H. and Leiter, E.: Hydronephrosis and polycythemia. Urology 21:345-350, 1983.

3. Hirsch, I.H., Schoeneman, M. and Leiter, E.: Intermittent versus continuous urinary perfusion of rabbit ileum and its clinical implications for continent ureterointestinal urinary diversion. Surgical Forum 34:693-695, 1983.

4. Hirsch, I.H. , Gibbons, W.E. and Lipshultz, L.I.: Treatment of male infertility by in-vitro fertilization, American Urological Association Sound Slide Series, AUA 0088, 1985.

5. Hirsch, I.H. , Lipshultz, L.I., Fujino, A. and Scardino, P.T.: Evaluation of the accessory sex glands in azoospermic males by transrectal ultrasonography. Surgical Forum 36:618-622, 1985.

6. Hirsch, I.H. and Lipshultz, L.I.: Transrectal ultrasonography: Elucidates the causes of male infertility. Masters in Urology 1:10-12, 1985.

7. Hirsch, I.H. , Gibbons, W.E., Lipshultz, L.I., Rossavik, I.K., Young, R.L., Poindexter, A.N., Dodson, M.G., and Findley, W.E.: In-vitro fertilization in couples with male factor infertility. Fertility and Sterility 45:659-664, 1986.

8. Fishman, I.J., Hirsch I.H. and Toombs, B.D.: Endourological reconstruction of posterior urethral disruption. Journal of Urology 137:283-286, 1987.

9. Hirsch I.H. and Lipshultz, L.I.: Medical treatment of male infertility. Urological Clinics of North America 14:307-321, 1987.

10. Hirsch, I.H. : Pharmacologic therapy of male infertility: Specific Treatment. Comprehensive Therapy 15(8):59-64, 1989.

11. Hirsch, I.H. and Choi, H.Y.: Quantitative testicular biopsy in congenital and acquired genital tract obstruction. Journal of Urology 143:311, 1990.

12. Hirsch, I.H. , Seager, S.W.J., Sedor, J., King, L., and Staas, W.E.: Electroejaculatory stimulation of quadriplegic male followed by pregnancy. Archives of Physical Medicine and Rehabilitation 71:54-57, 1990.

13. Hirsch, I.H. , Sedor, J., Callahan, H.J. Staas, W.E.: Systemic sperm autoimmunity in spinal cord injured men. Archives of Andrology 25:69-73, 1990.

14. Carroll, J.L, Baltish, M.H., Bagley, D.H., and the Jefferson Sexual Function Center: The Use of PotenTest in the Multi-disciplinary Evaluation of Impotence: Is it a Reliable Measure. J. Sex & Marital Therapy, 16:181-187, 1990.

15. Carroll, J.L., Ellis, M.D., Bagley, D.H., and Jefferson Sexual Function Center: Age-related changes in hormones in impotent men. Urology 36:42-46, 1990.

16. Hirsch, I.H. , Bagley, D.H., Rifkin, M., Bollinger, J., Merton, D.: Color Doppler imaging of the penile veins: Comparison with dynamic infusion cavernosometry and cavernosography. International Journal of Impotence Research 2:169-170, 1990.

*17. Hirsch, I.H. , Rosecrans, R.R., Sedor, J. and Jeyendran, R.S.: Biochemical analysis of human electroejaculates. Journal of Urology 145:73-76, 1991.

*18. Hirsch, I.H. , Lee, J., Allen, J., McCue P.A., and Staas, W.E.: Quantitative testicular biopsy in spinal cord injured men.: Comparison to fertile controls. Journal of Urology 146:337-341, 1991.

*19. Hirsch, I.H. , Sedor, J., Callahan, H.J. and Staas, W.E.: Antisperm antibodies in seminal plasma of spinal cord injured men. Urology 39:243-247, 1991.

*20. Fujino, A., Hirsch, I.H. , Lipshultz, L.I.: An aid of transrectal ultrasonography in the evaluation of ductal abnormalities in the azoospermic patient. Japanese Journal of Medical Ultrasonics 18:470-478, 1991.

*21. Hirsch, I.H. : Ins and outs of diagnosing impotence: Urologic Evaluation Audio - Digest: Urology, 14(10), October, 1991.

*22. Hirsch, I.H. , Sedor, J., Jeyendran, R.S., Staas, W.E.: The relative distribution of viable sperm in the antegrade and retrograde ejaculates obtained following electrostimulation. Fertility and Sterility 57:399-401, 1992.

*23. Hirsch, I.H. , Sedor, J., Shupp-Byrne, D., Chancellor, M.B., and Staas, W.E.: The spectrum of reproductive dysfunction in spinal cord injured men. Proceeding of electroejaculation interest group 1992.

*24. Chancellor, M.B., Hirsch, I.H. , Kiilholma, P., Staas, W.E.: Techniques of external sphincter balloon dilation. Urology, 40:308-310, 1992.

*25. Chancellor, M.D., McGinnis, D.E., Shenot, P.J., Hirsch, I.H. , Kiilholma, P.J.: Lyme cystitis and neurogenic bladder dysfunction secondary to Lyme disease. Lancet 339:1237-1238, 1992.

*26. Kiilholma, P., Chancellor, M.B., Makinen, J., Hirsch, I.H. , Klemi, P.: Complications of Teflon injection for stress urinary incontinence. Neuro-Urology and Urodynamics, 12:131-138, 1993.

*27. Chancellor, M.B., McGinnis, D.E., Shenot, P.J., Kiilholma, P., Hirsch, I.H. : Urinary dysfunction in Lyme disease. Journal of Urology 149:26-30, 1993.

*28. Hirsch, I.H., Kulp, D., McCue, P., Flanigan, M., Sedor, J., Stevenson, A., and Staas, W.E.: The value of quantitative testicular biopsy and DNA flow cytometry in predicting sperm recovery from electrostimulated ejaculates. Journal of Urology, Part 2, 149:1345-1349, 1993.

29. Hirsch, I.H. , Kulp, D., McCue P., Flanigan, M., Sedor, J. and Staas, W.E.: Validation of DNA flow cytometry analysis in the quantitative assessment of spermatogenesis: Comparison to the quantitative testicular biopsy. Journal of Urology 150:342-346, 1993.

*30. Sedor, J., Callahan, H.J., Perusia, B., Lattime, E., Hirsch I.H.: Fc-gamma-RIII and IgG levels in seminal plasma of men with immunologic infertility. Journal of Andrology 14:187-193, 1993.

*31. Hirsch, I.H. , Sedor, J., McCue, P., Staas, W.E.: Simplified and objective assessment of spermatogenesis in spinal cord injured men with flow cytometry analysis. Paraplegia 31:785-792, 1993.

*32. Chancellor, M.B., Karasick, S., Strup, S., Abdill, C.K., Hirsch, I.H. , Staas, W.E.: Transurethral balloon dilatation of the external urinary sphincter: effectiveness in spinal cord injured men with detrusor sphincter dyssynergia. Radiology 187:557-560, 1993.

*33. Chancellor, M.B., Rivas, D.A., Erhard, M.J., Hirsch, I.H. , Bagley, D.H.: Flexible cystoscopy during urodynamics of spinal cord injured patients. Journal of Endourology 7:531-535, 1993.

*34. Hirsch, I.H. : Male Reproductive Rehabilitation. The Andrology Report 2(2):4-7, 1993.

*35. Hirsch, I.H. , Sedor, J., McCue, P., Kulp-Hughes, D., Flanigan, M.: Objective assessment of spermatogenesis in men with functional and anatomic obstruction of the genital tract. International Journal of Andrology 17:29-34, 1994.

*36. White, J.L., Hirsch, I.H. , Bagley D.H.: Endoscopic urethroplasty following urethral avulsion. Urology 44:100-105, 1994.

37. Sedor, J. and Hirsch, I.H. : Office-based assessment of sperm autoimmunity. Journal of Urology 152:2017-2019, 1994.

*38. Chancellor, M.B., Erhard M., Hirsch, I.H. , Staas, W.E.: Prospective evaluation of Terazosin for the treatment of autonomic dysreflexia. Journal of Urology, 151:111-113, 1994.

*39. Hirsch, I.H. : Advances in Male Reproductive Rehabilitation. AUA Today __ 1-5, 1994.

*40. Hirsch, I.H. , Moreno, J., Gomella, L.G.: Facilitated implantation of the inguinal reservoir of the multi-component inflatable penile prosthesis. Journal of Urology 152:142-143, 1994.

*41. Hirsch, I.H. , Smith, R.L., Chancellor, M.B., Bagley, D.H., Carsello, J., Staas, W.E.: Use of intracavernous injection of Prostaglandin E-1 for neurogenic erectile dysfunction. Paraplegia 32:661-664, 1994.

*42. Hirsch, I.H. , Lotfi, M.A., Moreno, J., Gomella, L.G.: Controlled balloon dilatation of the retroperitoneal space for laparoscopic surgery. Journal of Laparoendoscopic Surgery 4:247-251, 1994.

*43. Gomella, L.G. and Hirsch I.H.: Extraperitoneal laparoscopic pelvic lymph node dissection using a new trocar mounted balloon device. Point of Origin (laparoscopy newsletter) 4:3-7, 1994.

*44. Hirsch, I.H. , Lotfi, M.A., Moreno, J., Gomella, L.G.: Non-insufflative laparoscopic access. Journal of Endourology 9:483-486, 1995.

*45. Lotfi, M.A., Varga, J., Hirsch, I.H. : Erectile dysfunction in systemic sclerosis. Urology 45:879-881, 1995.

*46. Hirsch, I.H. , Shenot, P., Gomella, L.G.: Radial dilatation in the implantation of the multi-component inflatable penile prosthesis. British Journal of Urology 75:92, 1995.

*47. Sedor, J.F. and Hirsch, I.H.: Evaluation of sperm morphology of electroejaculates of spinal cord injured men by strict criteria. Fertility and Sterility 63:1125-1128, 1995.

*48. Hirsch, I.H. : Spermatogenesis following spinal cord injury. Topics in SCI Rehabilitation 1:27-43, 1995.

*49. Moreno, J.G., Gomella, L.G., Hirsch, I.H., Bagley, D.H.: A novel prostatectomy technique: Transurethral electrovaporization of the prostate. Techniques in Urology 1:62-66, 1995.

*50. Watanabe, T., Chancellor, M.B., Rivas, D.A., Hirsch, I.H., Bennett, C.J., Finochiaro, M.V., Razi, S., Bennett, J.K., Green, B.G., Foote, J.E., Killorian, W., Juma, S., Lindsenmeyer, T., Lloyd, K.: Epidemiology of current treatment of sexual dysfunction in spinal cord injured men in the USA model spinal cord injury centers. Journal of Spinal Cord Medicine 19:186-189, 1996.

*51. Gomella, L.G., Abdel-Meguid, T.A., Lotfi, M.A., Hirsch, I. H., Albala, D., Manyak, M., Kozminski, M., Sosa, E., Stone, N.N.: Laparoscopic urologic surgery outcome assessment. Laparoscopic Surgery 7:77-86, 1997.

*52. Ismail, M., Abbott, L., Hirsch, I.H.: Experience with intracavernous PGE-1 in the treatment of erectile dysfunction: Dose considerations and efficacy. International Journal of Impotence Research 9:39-42, 1997.

*53. Hirsch, I.H. , Abdel-Meguid, T.A., Gomella, L.G.: Gasless laparoscopic varicocele ligation: New Instrumentation and technique for retroperitoneal and intraperitoneal approaches. Journal of Laparoendoscopic and Advanced Surgical Techniques 7:221-226, 1997.

*54. Abdel-Meguid, T., and Hirsch, I.H.: Non-insufflative extraperitoneal laparoscopic varicocele ligation. Techniques in Urology 2:217-221, 1997.

*55. Hirsch, I.H., Huang, B., Chancellor, M.B., Rivas, D.A., Salzman, S.K., Jost, L.K., Evenson, D.P.: Spermatogenesis in the early and chronic phases of experimental spinal cord injury in the rodent model. Journal of Andrology 20:63-71, 1999.

56. Shenot, P.J., Figueroa, E., Hirsch, I.H.: Meatoplasty for megalomeatus. Journal of Urology (in preparation).

57. Chiura, A., Wilkerson, J., Hirsch, I.H.: Gunshot wound to the glans penis: The importance of corporal exploration. Techniques in Urology 5:49-51, 1999.

58. Rajan, R., Hirsch, I.H.: Using a colonoscopy snare to safely remove large papillary bladder tumors. Techniques in Urology 4:208-210, 1998.

59. Hirsch, I.H., and Moy, L.: Glandular-tunical stabilization to repair the SST-deformity of the inflatable penile prosthesis. Techniques in Urology (submitted).

*60. Liberman, S.N., Gomella, L.G., and Hirsch, I.H.: Experience with Ultrex and Ultrex Plus inflatable penile prosthesis: new implantation techniques and surgical outcome. International Journal of Impotence Research 10:175-179, 1998.

61. Hirsch, I.H., Abdel-Meguid, T.A., Gomella, L.G.: Postsurgical outcomes assessment following varicocele ligation: Laparoscopic versus sub-inguinal approach. Urology 51:810-815, 1998.

62. Ismail, M.T., Sedor, J.F., Hirsch, I.H., Are sperm motion parameters influenced by varicocele ligation? Fertility and Sterility 71:886-890, 1999.

63. Elliot, S.P., Orejuela, F., Hirsch, I.H., Lipshultz, L.I., Lamb, D.J., Kim, E.D., Testis biopsy findings in the spinal injured patient. Journal of Urology (submitted).

64. Das, A., Soroush, M., Maurer, P., Hirsch, I.H.: Multicomponent penile prosthesis implantation under regional anesthesia. Techniques in Urology 5: 92-94, 1999.

65. Hirsch, I.H.: The scope of alternative and complementary therapy in urology. AUA News, September/October, 1999.

66. Halpern, E.J., Hirsch, I.H.,: Ultrasound guided transurethral incision of a Mullerian duct cyst for treatment of ejaculatory duct obstruction. American Journal of Radiology (submitted).

AUDIO-VISUALS

1. Hirsch, I.H.: Ins and outs of diagnosing impotence: Urologic Evaluation; Audio - Digest: Urology, 14(10), October 1991.

2. Hirsch, I.H., Moreno, J.G., Lotfi, M.A., Gomella, L.G.: Extraperitoneal unilateral varicocele ligation without pneumoperitoneum (1994).

3. Hirsch, I.H., Lotfi, M.A., Moreno, J.G., Gomella, L.G.: Gasless varicocele ligation using the Laparolift/Laparofan system. (1994).

4. Gomella, L.G., Moreno, J.G., Lotfi, M.A., Hirsch, I.H.: Extraperitoneal laparoscopic lymph node dissection with preliminary dissection using a new trocar mounted balloon device (1994).

5. Hirsch, I.H., Moreno, J.G., Gomella, L.G.: The concept of controlled distention for inflatable penile prosthesis implantation (1995). Selected by: *Ortho-McNeil American Urological Association Video Library, *Department of Urology, University of Chicago.

6. Hirsch, I.H.: Color Doppler imaging in the evaluation of impotence. Ultrasound video classroom. Videotape Catalogue. The Jefferson Ultrasound Research and Education Institute. Thomas Jefferson University, 1994.

7. Hirsch, I.H., Moreno, J.G., Gomella, L.G.: The concept of controlled distention for inflatable penile prosthesis implantation. Video Urology Times. Volume 8, Program 4, 1995.

INVENTIONS

1. Radial Distension of Soft Tissue Space Using a Finger Guided Distension Balloon. (Patent issued: 6/27/96).

BOOK CHAPTERS

1. Gibbons, W.E., Hirsch, I.H. and Lipshultz, L.I.: Male factor in IVF. in Foundations of In-Vitro Fertilization, Chapter 14, pgs 170-176, Fredericks, C.M., Paulson, J.D., DeCherney, A.H. (Eds.) Hemisphere Publishing Corp., Cambridge, 1987.

2. Fishman, I.J., Hirsch, I.H., and Toombs, B.D.: Endourological reconstruction of posterior urethral disruption. In: Concurrent Operative Urology 1991, E.D., Whitehead (Ed) J.B. Lippincott, Co., Philadelphia, 1991.

3. Hirsch, I.H.: Commentary: Testicular Biopsy. In Current Operative Urology, Chapter 19, pgs. 307-312, Whitehead, E.D. (Ed) , J.B. Lippincott Company, Philadelphia, 1992.

ABSTRACTS:

1. Feit, J., Hirsch, I.H., Mieza, M. and Leiter, E.: The effect of the “prep” on the quality of intravenous urography. American Urological Association 77:242, 1982.

2. Schoeneman, M., Hirsch, I.H.., and Leiter, E.: Water and solute fluxes across isolated rabbit ileum: model of ileal bladder. The Society for Pediatric Research, 1984.

3. Hirsch, I.H., Schoeneman, M. and Leiter, E.: Water of solute fluxes across isolated rabbit ileum. A model of continent uretero-intestinal urinary diversion. Journal of Urology 131:396A, 1985.

4. Hirsch, I.H., Gibbons, W.E. and Lipshultz, L.I.: The role of in-vitro fertilization in the oligospermia male. Journal of Urology 133:161A, 1985.

5. Hirsch, I.H., Gibbons, W.E. and Lipshultz, L.I.: Sperm penetration assay: a predictor of successful in-vitro fertilization for male factor infertility. Journal of Andrology 6:41, 1985.

6. Hirsch, I.H., Gibbons, W.E., Lipshultz, L.I., Young, R., Dodson, M., Poindexter, A., and Findley, W.: Solitary male factor infertility: Prognosis in in-vitro fertilization. American Fertility Society, Chicago, Illinois, 1985.

7. Hirsch, I.H., Choi, H.Y., Mulholland, S.G.: Quantitative testicular biopsy in congenital and acquired genital tract obstruction. Journal of Andrology, 9:32, 1988.

8. Hirsch, I.H., Choi, H.Y., Mulholland, S.G.: Quantitative testicular biopsy in spinal cord injury. Journal of Urology 139:411A, 1988.

9. Hirsch, I.H., Seager, S.W.J., Sedor, J., Callahan, H.J.: Reproductive potential of men with ejaculatory failure. International Forum of Andrology, pg. 149, 1989.

10. Hirsch, I.H., Seager, S.W.J., Sedor, J., Staas, W.E.: Reproductive rehabilitation of spinal cord men. Journal of Urology 141:337A, 1989.

11. Walker, S.R., Hirsch, I.H.: Percutaneous (non-incisional) bladder neck suspension for urinary stress incontinence. Journal of Urology 141:425A, 1989.

12. Hirsch, I.H., Sedor, J., Goldfarb, A.F., King, L., Packin, G., Wu, C.H.: Intrauterine insemination with washed sperm for the treatment of male infertility. Journal of Urology 141:445A, 1989.

13. Nord, R.G., Hirsch, I.H., Knobler, R.L., Lublin, F.D.: Urodynamic assessment of patients with exacerbated multiple sclerosis. Journal of Urology 141:568A, 1989.

14. Hirsch I.H., Rosecrans, R.R., Sedor, J., Jeyendran, R.S.: Biochemical analysis of human electroejaculates. Journal of Andrology 10: 32P, 1989.

15. Hirsch, I.H., Sedor, J., Callahan, H.J., Staas, W.E.: Sperm autoimmunity in spinal cord injured men. Journal of Andrology 10:33P,1989.

16. Hirsch, I.H., Lee, J., McCue, P., Sedor, J., Seager, S.W.J., Staas, W. E.: Quantitative testicular biopsy as a predictor of sperm concentration in electrostimulated ejaculates of spinal cord injured men. Journal of Andrology 10:32P, 1989.

17. Seager, S.W.J., Halstead, L.S., Ohl, D.A., Bennett, C.J., Lipshultz, L.I., Belker, A.M., Hirsch, I.H., McGuire, E.J., Edmonds, P.A., Krishnan, K.R., Hargreave, P.B., and McDermott, T.: Electroejaculation and its utilization for fertility evaluation in 266 spinal cord injured men. American Spinal Injury Association Abstracts Digest, 1990.

18. Hirsch, I.H., Sedor, J., Jeyendran, R.S., and Staas, W.E.: The relative distribution of viable sperm in antegrade and retrograde ejaculates during electroejaculation. Journal of Andrology ll:P-51, 1990.

19. Hirsch, I.H., Bagley, D.H., Christinzio, J.: Dosage considerations in the self-administration of Prostaglandin E-1 for erectile dysfunction. Journal of Urology 143:305A 1990.

20. Hirsch, I.H., Lee, J., Allen, J., McCue, P., Staas, W.E.: Quantitative testicular biopsy in spinal cord injury men: Comparison to fertile controls. Journal of Urology 143:345A 1990.

21. Chancellor, M.B., Hills, E., Schwartz, L.M., Hirsch, I.H.: Treatment of erectile dysfunction in males with spinal cord injury using the vacuum constriction device. American Spinal Injury Association Abstracts, (1991) .

22. Hirsch I.H., Christinzio, J., Bagley, D.H., Chancellor, MB, and Staas, W.E. Treatment of erectile dysfunction in spinal cord injury men with prostaglandin E-1, dosage considerations, safety, efficacy American Spinal Injury Association Abstracts, (1991).

23. Sedor, J., Hirsch, I.H., Callahan, H.J. Comparison of a few techniques with sperm antibody screening. Journal of Andrology 12: P-46, 1991.

24. Hirsch, I.H., McCue, P.A., Conn, R.B., Flanigan, M.T., Staas, W.E.: Quantitative testicular biopsy in spinal cord injured men: comparison of quantitative micrometric and cytometric analysis. Journal of Andrology 12:P-36, 1991.

25. White, J.L., Hirsch, I.H., Bagley, D.H.: Posterior urethral avulsion. Journal of Endourologic Repair of Urology 145:415A, 1991.

26. Patrick, J.S., Chancellor, M.B, Hirsch, I.H., Blaivas, J.G., Bhansali, L.D., Kaplan, S.A., Benach, J.L., Fremont-Smith, M.: Bladder infection by the Lyme spirochete. Journal of Urology 145:235A, 1991.

27. Hirsch, I.H., Sedor, J., Kulp, D., Flanigan, M.M., Staas, W.E.: Quantitative assessment of the germinal epithelium as a predictor of total sperm yield in electroejaculates. Journal of Urology 147:2, 1992.

28. Chancellor, M.B., Kiilholma, P., Hirsch, I.H.: Bladder physiology in experimental rat spinal trauma. Journal of Urology 147:312A, 1992.

29. Chancellor, M.B., Erhard, M.J., Abdill, C.K., Goodman, C., Hirsch, I.H., Staas, W.E.: Prospective comparison of external sphincter balloon dilatation and prosthesis placement with external sphincterotomy in spinal cord injured men. Journal of Urology 147:400A, 1992.

30. Erhard, M.J., Chancellor, M.B., Abdill, C.K., Kiilholma, P., Hirsch, I.H., Staas, W.E.: Membranous urethral prosthesis of neurogenic bladder. Journal of Urology l47:439A, 1992.

31. Chancellor, M.B., Erhard, M.J., Abdill, C.K., Goodman, C., Hirsch, I.H., Staas, W.E.: Prospective evaluation of external sphincter balloon dilatation and prosthesis placement as alternatives to external sphincterotomy. Journal of the American Paraplegia Society 15: 102, 1992.

32. Chancellor, M.B., Erhard, M.J., Hill, K., Hirsch, I.H., Staas, W.E.: Prospective open-label evaluation of Terazosin in the treatment of autonomic dysreflexia. Journal of the American Paraplegia Society 15:106, 1992.

33. Erhard, M.J., Chancellor, M.B., Abdill, C.K., Hirsch, I.H., Bagley, D.H.: Flexible cystoscopy during urodynamics of spinal cord injured patients. Journal of American Paraplegia Society 15:133, 1992.

34. Chancellor, M.B., Karasick, S., Abdill, C.K., Hirsch, I.H., Staas, W.: Assessment of alternative therapies to sphincterotomy sphincter prosthesis placement and balloon dilatation. Neuro-Urology & Urodynamics 11:331, 1992.

35. Chancellor, M.B., Huang, B., Kiilholma, P., Hirsch, I.H.: Micturition patterns in experimental rat spinal trauma. Neuro-Urology & Urodynamics. Annual Meeting of the International Continence Society, Halifax, Canada, September 1-4, 1992.

36. Hirsch, I.H., Sedor, J., Kulp, D., McCue, P.: Objective assessment of spermatogenesis in men with functional and anatomic genital tract obstruction. Journal of Andrology

14:P-51, 1993.

37. Sedor, J. Carsello, J.M., Shupp-Byrne, D., Hirsch, I.H.: Evaluation of sperm morphology of electroejaculates by strict Kruger criteria. Journal of Andrology 14:P-60, 1993.

38. Sedor, J., Andrei, V., Shupp-Byrne, D., Hirsch, I.H.: Prevalence of leukospermia in electroejaculates of spinal cord injured (SCI) men. Journal of Andrology 14:P-60, 1993.

39. Hirsch, I.H., Chancellor, M.B., Huang, B., Salzman, S., Evenson, D.: Spermatogenesis following experimental spinal cord injury (SCI). The American Fertility Society, Abstracts of the Scientific Sessions, P-207, 1993

40. Hirsch, I.H., Alexander, A., Weitzel, A., Schanne, F., Carsello, J., Bagley, D.H.: Ultrasound monitoring of patients treated with chronic intracavernous Prostaglandin E-1. Journal of Urology 149:344A, 1993.

41. Hirsch, I.H., Kulp, D., Sedor, J. McCue, P., Flanigan, M.: Validation of flow cytometry analysis (FCA) in the assessment of spermatogenesis: Comparison with quantitative testicular biopsy. Journal of Urology 149:435A, 1993.

42. Gomella, L.G., Lotfi, M.A., Moreno, J.G., Hirsch, I.H.: Extraperitoneal laparoscopic lymph node dissection with preliminary dissection using a new trocar mounted balloon device. Journal Urology 151:210A, 1994.

43. Hirsch, I.H., Moreno, J.G., Lotfi, M.A., Gomella, L.G.: Extraperitoneal unilateral varicocele ligation without pneumoperitoneum. Journal of Urology 151:222A, 1994.

44. Hirsch, I.H., Lotfi, M.A., Moreno, J.G., Gomella, L.G.: Comparison of outcome parameters in open and laparoscopic varicocele ligation. Journal of Urology 151:310A, 1994.

45. Moreno, J.G., Lotfi, M.A., Gomella, L.G., Hirsch, I.H.: Gasless laparoscopic varicocele ligation. Journal of Urology 151:342A, 1994.

46. Rivas, D.A., Chancellor, M.B., Erhard, M.J., Huang, B., Hirsch, I.H., Salzman, S.K.: Comparison of erectile response to intraurethral, topical, and intracorporal pharmacotherapy in the rat model of spinal cord injury. Journal of Urology 151:495A, 1994.

47. Hirsch, I.H., Shenot, P.J., Chancellor, M.B., Sedor, J., Staas, W.E.: Simplified and objective assessment of spermatogenesis in spinal cord injured men by flow cytometry analysis. Journal of the American Paraplegia Society 17:92, 1994.

48. Hirsch, I.H., Shenot, P.J., Huang, B., Rivas, D.A., Chancellor, M.B., Salzman, S.K., Evenson, D.P.: Spermatogenesis in the rodent model following experimental spinal cord injury. Journal of the American Paraplegia Society 17:93, 1994.

49. Rivas, D.A., Chancellor, M.B., Erhard, M.J., Huang, B., Hirsch, I.H., Salzman, S.F.: Comparison of erectile response to the intracorporal, topical and intraurethral application of vasoactive substances in the rat model of spinal cord injury. Journal of the American Paraplegia Society 17:104, 1994.

50. Hirsch, I.H., Chancellor, M.B., Shenot, P.J., Rivas, D.A., Staas, W.E.: Enhanced fertility in spinal cord injured men following external sphincter reduction procedures. Journal of the American Paraplegia Society 17:121, 1994.

51. Hirsch, I.H., Moreno, J.G., Gomella, L.G.: The concept of controlled distention for inflatable penile prosthesis implantation. Journal of Urology, 153:206A, 1995.

52. Liberman, S.N., Gomella, L.G., Hirsch, I.H.: Experience with the multi-component inflatable prosthesis: New implantation technique and surgical outcome. Journal of Urology, 153:322A, 1995.

53. Hirsch, I.H., Huang, B., Chancellor, M.B., Rivas, D.A., Evenson, D.P. Salzman, S.K.: Spermatogenesis in the rodent model of acute and chronic experimental spinal cord injury (SCI). Journal of Urology, 153:332A, 1995.

54. Gomella, L.G., Abdel-Meguid, T., Hirsch, I.H., Albala, D., Manyak, M., Richardson, B., Kozminski, M., Sosa, R.E., Stone, N.N.: Laparoscopic urologic surgery: Continued improvement in outcome. Journal of Urology, 153:358A, 1995.

55. Hirsch, I.H., Fishman, I.J., and Toombs, B.T.: Endourologic reconstruction of posterior-urethral avulsion. Third World Congress on Endourology, Abstract C-22, 1995.

56. Sedor, J.F., Shupp-Byrne, D.E., Hirsch, I.H.: Measurement of neutral a - glucosidase in electroejaculation of spinal cord injured men. Journal of Andrology 16:46, 1995.

57. Steiner, J.E., Hirsch, I.H., van Arsdalen, K.N., Wysocki, C.J.: Specific androsterone anosmia in patients with impaired sperm production. Journal of Chemical Senses, 21:5, 1996.

58. Hirsch, I.H., Feld, R.I., Gomella, L.G., McCue, P.T.: Testicular microlithiasis (TML) in men with azoospermia and severe oligospermia. American Society of Andrology, Baltimore, MD, February 23-25, 1997.

59. Hirsch, I.H., Ismail, M.T., Sedor, J.F.: Are sperm motion parameters influenced by varicocele ligation? Journal of Andrology, 18:47, 1997.

60. Feld, R.I., Hirsch, I.H., Alexander, A.A., Nazarian, L.N., Needleman, L., Gomella, L.G.: Testicular sonographic findings in infertility. Radiology 205:280, 1997.